Data detailed in "Infection, inflammation, and bone regeneration: a paradoxical relationship" have been presented. "Various strategies have been developed to promote bone regeneration in the craniofacial region. Most of these interventions utilize implantable materials or devices," scientists in Lexington, Kentucky report (see also Biomedical Engineering).
"Infections resulting from colonization of these implants may result in local tissue destruction in a manner analogous to periodontitis. This destruction is mediated via the expression of various inflammatory mediators and tissue-destructive enzymes. Given the well-documented association among microbial biofilms, …

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